Gastruloids are three-dimensional aggregates of embryonic stem cells. Gastruloids can generate polarised gene expression, establish spatially organised germ layers and undergo morphological elongation. In both their spatial and temporal progression, they mimic features of early embryonic patterning. Therefore, gastruloids can be used to study early developmental processes such as gastrulation and axial extension that are otherwise difficult to access in vivo. Gastruloids offer a minimalistic system that works under defined conditions. The system complements other in vitro methods as a bottom-up approach for studying development.
The instructors will discuss the background and principles of gastruloid systems, including a detailed explanation of the protocol, troubleshooting steps and tips to ensure maximal reproducibility.
1. To understand the principles of early embryonic development
2. To learn how to set up and maintain gastruloids from embryonic stem cells
3. To learn about ways to analyse image data generated from gastruloids by qualitative and quantitative methods
4. To gain knowledge about the use of gastruloids in research and their potential applications in drug development and treating disease
Dr Peter Baillie-Johnson
Postdoctoral Researcher, University of Cambridge
Mr Stefano Vianello
PhD Student, École polytechnique fédérale de Lausanne, Switzerland
Dr David Turner
Group Leader, University of Liverpool
Professor Jenny Nichols
Principal Investigator, University of Cambridge
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With this course you get our exclusive CamBioScience membership for free and receive an automatic 10% discount on your registration fee. (Included in the pricing below)
|Fees*||Until 04.10.19||From 05.10.19|
|Academia||£697.50 +VAT||£837.00 +VAT|
|Industry||£1185.75 +VAT||£1422.90 +VAT|
Registration fees include: course materials, instruction from world-leading experts, hot meals, formal dinner on the first evening and refreshments.
To register, please click below and fill in the registration form. You will then receive an email confirmation in which you will be able to choose a payment method (pay by card online, or receive an invoice to process payment by bank transfer).